KIMA NEWS

Seoul St. Mary’s Hospital, The Catholic University of Korea, Cheol-woo Yang the director of the organ transplantation department. “Kidney transplants with different blood type, no difference in survival rate.”

October 23, 2019

“4 out of every 10 people with chronic kidney disease who received kidney transplants at our center last year is blood Type incompatible transplant, which is higher than the national average of 35 percent, for example, the patient is types A and the donor is type B. “Yang Cheol-woo, director of the organ transplant department at Catholic University of Korea Seoul St. Mary’s Hospital, said, “Due to advances in medicine and medical technology, the difference in the survival rate of blood type incompatible transplant has disappeared.” And, “There is no need to hesitate about the transplant because the blood type is different from the donor.” The hospital’s organ transplant center achieved 100 cases in January 2016 and 200 cases in December last year after it successfully transplanted its first blood type non-conforming kidneys in May 2009. Contributors were spouses (49.5 percent), parents and children (20 percent), and siblings (17.5 percent). The center has also recently succeeded for simultaneous transplantation of blood type-appropriate liver and blood type incompatible kidneys from two people.

The 200th patient who received blood type incompatible kidney transplant is a 59-year-old woman who has been on peritoneal dialysis since nine years ago. Although her blood type was different from her daughter, who got her kidneys with type O, fortunately, her antibody retention strength for type A blood was 1:128, which was only half the normal level (1:256). In other words, there are relatively few antibodies that cause rejection after transplantation. A month before the transplant, the medical team injected “Mabthera,” an antibody-producing inhibitor in the blood. She then removed her own plasma containing antibodies by taking the blood outside, and performed plasma exchange six times, one of the main ingredients of the plasma, such as albumin or other people’s plasma, which is suitable for blood type, to lower the antibody factor to below 1:16. Plasma is a transparent neutral liquid excluding red blood cells, white blood cells, and platelets, and serves to transport nutrients, hormones, antibodies, and wastes and maintain osmotic pressure and body temperature. He said that even patients with high antibody levels, or high antibody levels, will see little difference in survival rate if the potency is reduced by increasing the number of plasma exchanges.

https://www.sedaily.com/NewsView/1VDZF8TNHK


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