Anti-aging research center of Arumdaun Nara Dermatology·Plastic surgery Clinic has released various theses and seminar in relation with the development of global wrinkle treatment, lifting technology as well as domestically for 20 years. 11 theses among 12 papers announced domestically in relation with Ultherapy and Thermage, which are representative premium wrinkle treatment, were announced by Arumdaun Nara dermatology. It is very exceptionally that over 90% of theses are released by one hospital. In addition, it is evaluated it is writing a history of anti-aging by publishing a specialized medical book on core thread lifting. It announced the comparison analysis of 3 treatments such as Tune Face, Thermage, Ultherapy using histometric techniques at American Academy of Dermatology (AAD) meeting held in San Diego in March 2018. The Tune Face lifting is a wrinkle treatment laser which injects heat energy of 40.68MHz using Unipolar which is different from other existing wrinkle treatment device, it can deliver the most heat energy within the range not causing adverse effect. Because the treatment spot is kept in a cold vacuum, the patients can receive the treatment comfortably without anesthesia or pain. Asia’s first 40.68MHz wrinkle elasticity joint research conducted with Alma, Israel was announced as SCI class thesis in 2017.